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There are 350 million positives with Hepatitis B viruses (HBV) globally, and more than one million people die annually from Hepatitis B or its associated diseases. In China , there are 120 million positives with HBV.



The drug design is based on:

  1. Proprietary Structure-based Drug Design
  2. Experience in the study of creatine kinase analogue and its substrate
  3. Comparison of 3D structures between HIV reverse transcriptase and HBV polymerase

The advantages:

  • Good oral availability and high efficacy in comparison to Lamivudine
  • Reduced the toxicity and drug resistance

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